长期暴露下纳米二氧化钛对典型淡水藻体砷累积与生物转化的影响

以铜绿微囊藻(Microcystis aeruginosa)和斜生栅藻(Scenedesmus obliquus)为研究对象,通过室内培养实验,研究了长期暴露下纳米二氧化钛(nano-TiO_2)对五价砷[As(Ⅴ)]在典型淡水藻体中累积与生物转化的影响.结果表明不同藻类对无机砷的吸收和转化能力差异很大.长期暴露下斜生栅藻累积的砷(As,以DW计,下同)高达(819.66±11.25)μg·g-1,比铜绿微囊藻累积的As[(355.95±8.31)μg·g-1]高2倍多.Nano-TiO_2可增加藻体对As的吸收累积,降低了培养基中As的含量.同时,nano-TiO_2可增加藻体对As(Ⅴ)的生化转化;其中,铜绿微囊藻中有机砷以二甲基砷(DMA)为主,而斜生栅藻中有机砷以一甲基砷(MMA)为主.另外,长期暴露下nano-TiO_2处理的铜绿微囊藻和斜生栅藻向培养基释放的甲基砷小于对照组,表明长期暴露中的nano-TiO_2不能促进藻体内甲基砷的释放.研究结果可促进nano-TiO_2与As相互作用时生态风险的理解.     

2014年APEC期间北京市PM10和PM2.5氧化性损伤能力研究

为评估APEC会议期间联防联控措施对北京市大气可吸入颗粒物毒性的影响,采集2014年APEC会议前后3个月北京市大气PM₁₀和PM_2.5样品,应用质粒DNA损伤评价法来研究其氧化性损伤能力. 结果表明,APEC会议期间PM₁₀对DNA的损伤率高于PM_2.5,颗粒物对 DNA损伤率随剂量的增加而增加. 本研究用TD30值来指示颗粒物氧化性损伤能力,TD30为引起30%的DNA损伤率所需要的颗粒物剂量（单位为 μg·mL^-1）,TD30值越低,颗粒物氧化性损伤能力越强,APEC会议前后样品的TD30值表现为 APEC期间（11月）>APEC前（10月）>APEC后（12月）,说明氧化能力APEC后 >APEC前 >APEC期间. 用PM₁₀质量浓度乘上其在250 μg·mL^-1 剂量下的DNA损伤率得到颗粒物暴露毒性指数TI（toxic index）,与往年具有代表性月份样品的数据对比,TI大小顺序为2004年 >2014年 >2008年,说明大气中颗粒物暴露毒性随着政策控制力度的加大而降低.     

New York City Environmental Justice Alliance Waterfront Justice Project

This paper reviews key challenges and opportunities addressed by the New York City Environmental Justice Alliance's (NYC-EJA) Waterfront Justice Project, a citywide campaign to promote climate resilience and sustainability in urban industrial waterfront communities of New York City. NYC-EJA is a non-profit membership-driven network linking grassroots organisations from low-income neighbourhoods and communities of colour in their struggle for environmental justice. The Waterfront Justice Project is documenting community vulnerability in the context of climate change impacts, sources of industrial pollution, and demographic and socio-economic trends. This campaign is enabling community-based organisations, environmental justice communities, city planners, local and state government agencies, local business-owners, and other stakeholders to work in partnership to achieve community resilience while advocating for local jobs and promoting best practices in pollution prevention. New York City's waterfront policies ease the siting and clustering of public infrastructure, water pollution control plants, waste transfer stations, energy facilities, and heavy manufacturing uses in six areas designated as Significant Maritime and Industrial Areas (SMIAs). The SMIAs are located in environmental justice communities, largely low-income communities and communities of colour, in the South Bronx, Brooklyn, Queens, and Staten Island. New York City's local waterfront land use and zoning policies create cumulative risk exposure not only to residents and workers in the host waterfront communities, but also, in the event of storm surge or sea-level rise, to neighbouring, upland communities.     

基于贝叶斯网络的航空维修人因可靠性分析

根据维修人为因素分析和分类扩展系统的框架选取影响因素,在航空维修领域应用贝叶斯网络进行人因可靠性分析,建立飞机维修效能模型,直观地表示影响因素与维修效能之间的关系。同时以目视检测为例,结合专家意见确定随机影响因素,通过专家访谈、事故报告、调查问卷、操作记录等渠道获取数据,得出条件概率表,进而建立目视检测表现模型,展示贝叶斯网络的建模流程。案例研究结果表明,组织文化、视觉信息、设备、疲劳、检测距离等因素对目视检测表现的影响非常显著,欲改善目视检测表现,必须对多影响因素进行综合管理。     

页岩气压裂作业人因失误结构化辨识方法研究

为提高页岩气压裂作业人因失误辨识结果的全面性和针对性,建立一种结构化的人因失误辨识方法。通过概括辨识阶段的作业流程,建立作业人员行为模型,概述作业人员的行为阶段。利用筛选出的引导词辨识行为阶段人因失误。将该方法应用于页岩气压裂过程的替液阶段。结果表明,用引导词能明确辨识方向,减少头脑风暴时间以及对专家知识的依赖;辨识过程的动态调整能改善认知可靠性,使更多人因失误模式(与传统CREAM方法相比)被辨识出来。     

京津冀地区面向人居环境之水安全格局初探

采用文献法对近年京津冀水资源、水环境、水污染、水灾害、水管理等水安全情势进行相关数据分析,从总体上显示出水危机问题和京津冀地区快速城市化发展的关联性.结果表明:1)京津冀城市群必须向节水型社会模式转型;2)建立区域及城市间的协调机制,才能有效克服流域与区域等级的水问题;3)实现京津冀地区水安全格局的治理行动计划网络,提出保护恢复体系、净化循环体系、限制节约体系、调度再造体系、蓄滞防洪减灾体系五大体系.     

基于改进的HFACS和SPA的矿山安全人因分析

为了更好地服务于矿山安全管理,同时解决矿山人为因素调查、分析和评价方面存在的缺失,对部分矿山事故进行了统计分析,研究了诱发事故发生的人因因素,并分析了各因素发生的原因。在此基础上,结合对部分矿山安全管理现状的研究,建立了矿山HFACS分析模型。该模型包括5类事故致因、24个人因因素。应用该模型,结合集对分析方法,可实现矿山人因因素定量与定性分析。以陕西省某矿山为例,建立了该矿山的HFACS模型。采用专家评分法、层次分析法确定各因素的权重,计算出系统的联系度表达式。利用该表达式对该矿山的集对势、联系度、不确定性和悲观势进行了分析。结果表明,该矿山人因安全状况良好,个别人因因素指标需要改善和提高。矿山HFACS模型可以很好地涵盖矿山事故中的人因因素,通过对矿山人因现状的集对分析,可以有效提高矿山安全性。     

Lower Leg Injury Reference Values and Risk Curves from Survival Analysis for Male and Female Dummies: Meta-analysis of Postmortem Human Subject Tests

Objective: Derive lower leg injury risk functions using survival analysis and determine injury reference values (IRV) applicable to human mid-size male and small-size female anthropometries by conducting a meta-analysis of experimental data from different studies under axial impact loading to the foot–ankle–leg complex.

Methods: Specimen-specific dynamic peak force, age, total body mass, and injury data were obtained from tests conducted by applying the external load to the dorsal surface of the foot of postmortem human subject (PMHS) foot–ankle–leg preparations. Calcaneus and/or tibia injuries, alone or in combination and with/without involvement of adjacent articular complexes, were included in the injury group. Injury and noninjury tests were included. Maximum axial loads recorded by a load cell attached to the proximal end of the preparation were used. Data were analyzed by treating force as the primary variable. Age was considered as the covariate. Data were censored based on the number of tests conducted on each specimen and whether it remained intact or sustained injury; that is, right, left, and interval censoring. The best fits from different distributions were based on the Akaike information criterion; mean and plus and minus 95% confidence intervals were obtained; and normalized confidence interval sizes (quality indices) were determined at 5, 10, 25, and 50% risk levels. The normalization was based on the mean curve. Using human-equivalent age as 45 years, data were normalized and risk curves were developed for the 50th and 5th percentile human size of the dummies.

Results: Out of the available 114 tests (76 fracture and 38 no injury) from 5 groups of experiments, survival analysis was carried out using 3 groups consisting of 62 tests (35 fracture and 27 no injury). Peak forces associated with 4 specific risk levels at 25, 45, and 65 years of age are given along with probability curves (mean and plus and minus 95% confidence intervals) for PMHS and normalized data applicable to male and female dummies. Quality indices increased (less tightness-of-fit) with decreasing age and risk level for all age groups and these data are given for all chosen risk levels.

Conclusions: These PMHS-based probability distributions at different ages using information from different groups of researchers constituting the largest body of data can be used as human tolerances to lower leg injury from axial loading. Decreasing quality indices (increasing index value) at lower probabilities suggest the need for additional tests. The anthropometry-specific mid-size male and small-size female mean human risk curves along with plus and minus 95% confidence intervals from survival analysis and associated IRV data can be used as a first step in studies aimed at advancing occupant safety in automotive and other environments.     

Using Sound to Reduce Visual Distraction from In-vehicle Human–Machine Interfaces

Objective: Driver distraction and inattention are the main causes of accidents. The fact that devices such as navigation displays and media players are part of the distraction problem has led to the formulation of guidelines advocating various means for minimizing the visual distraction from such interfaces. However, although design guidelines and recommendations are followed, certain interface interactions, such as menu browsing, still require off-road visual attention that increases crash risk. In this article, we investigate whether adding sound to an in-vehicle user interface can provide the support necessary to create a significant reduction in glances toward a visual display when browsing menus.

Methods: Two sound concepts were developed and studied; spearcons (time-compressed speech sounds) and earcons (musical sounds). A simulator study was conducted in which 14 participants between the ages of 36 and 59 took part. Participants performed 6 different interface tasks while driving along a highway route. A 3 × 6 within-group factorial design was employed with sound (no sound /earcons/spearcons) and task (6 different task types) as factors. Eye glances and corresponding measures were recorded using a head-mounted eye tracker. Participants’ self-assessed driving performance was also collected after each task with a 10-point scale ranging from 1 = very bad to 10 = very good. Separate analyses of variance (ANOVAs) were conducted for different eye glance measures and self-rated driving performance.

Results: It was found that the added spearcon sounds significantly reduced total glance time as well as number of glances while retaining task time as compared to the baseline (= no sound) condition (total glance time M = 4.15 for spearcons vs. M = 7.56 for baseline, p =.03). The earcon sounds did not result in such distraction-reducing effects. Furthermore, participants ratings of their driving performance were statistically significantly higher in the spearcon conditions compared to the baseline and earcon conditions (M = 7.08 vs. M = 6.05 and M = 5.99 respectively, p =.035 and p =.002).

Conclusions: The spearcon sounds seem to efficiently reduce visual distraction, whereas the earcon sounds did not reduce distraction measures or increase subjective driving performance. An aspect that must be further investigated is how well spearcons and other types of auditory displays are accepted by drivers in general and how they work in real traffic.     

Development of a Computationally Efficient Full Human Body Finite Element Model

Introduction: A simplified and computationally efficient human body finite element model is presented. The model complements the Global Human Body Models Consortium (GHBMC) detailed 50th percentile occupant (M50-O) by providing kinematic and kinetic data with a significantly reduced run time using the same body habitus.

Methods: The simplified occupant model (M50-OS) was developed using the same source geometry as the M50-O. Though some meshed components were preserved, the total element count was reduced by remeshing, homogenizing, or in some cases omitting structures that are explicitly contained in the M50-O. Bones are included as rigid bodies, with the exception of the ribs, which are deformable but were remeshed to a coarser element density than the M50-O. Material models for all deformable components were drawn from the biomechanics literature. Kinematic joints were implemented at major articulations (shoulder, elbow, wrist, hip, knee, and ankle) with moment vs. angle relationships from the literature included for the knee and ankle. The brain of the detailed model was inserted within the skull of the simplified model, and kinematics and strain patterns are compared.

Results: The M50-OS model has 11 contacts and 354,000 elements; in contrast, the M50-O model has 447 contacts and 2.2 million elements. The model can be repositioned without requiring simulation. Thirteen validation and robustness simulations were completed. This included denuded rib compression at 7 discrete sites, 5 rigid body impacts, and one sled simulation. Denuded tests showed a good match to the experimental data of force vs. deflection slopes. The frontal rigid chest impact simulation produced a peak force and deflection within the corridor of 4.63 kN and 31.2%, respectively. Similar results vs. experimental data (peak forces of 5.19 and 8.71 kN) were found for an abdominal bar impact and lateral sled test, respectively. A lateral plate impact at 12 m/s exhibited a peak of roughly 20 kN (due to stiff foam used around the shoulder) but a more biofidelic response immediately afterward, plateauing at 9 kN at 12 ms. Results from a frontal sled simulation showed that reaction forces and kinematic trends matched experimental results well. The robustness test demonstrated that peak femur loads were nearly identical to the M50-O model. Use of the detailed model brain within the simplified model demonstrated a paradigm for using the M50-OS to leverage aspects of the M50-O. Strain patterns for the 2 models showed consistent patterns but greater strains in the detailed model, with deviations thought to be the result of slightly different kinematics between models. The M50-OS with the deformable skull and brain exhibited a run time 4.75 faster than the M50-O on the same hardware.

Conclusions: The simplified GHBMC model is intended to complement rather than replace the detailed M50-O model. It exhibited, on average, a 35-fold reduction in run time for a set of rigid impacts. The model can be used in a modular fashion with the M50-O and more broadly can be used as a platform for parametric studies or studies focused on specific body regions.